NUR 550 Evidence-Based Practice Project Proposal – Assignment

NUR 550 Evidence-Based Practice Project Proposal – Assignment

NUR 550 Evidence-Based Practice Project Proposal – Assignment

Learners will select a valid nursing practice problem for an evidence-based practice project proposal. The project will be completed in sections, beginning in NUR-550 and culminating in a final written paper detailing the evidence-based practice proposal in NUR-590. NUR 550 Evidence-Based Practice Project Proposal – Assignment

NUR 550 Evidence-Based Practice Project Proposal – Assignment

The purpose of this assignment is to select a relevant nursing practice problem for your evidence-based practice project proposal. To identify a relevant problem, consider problems generally faced in nursing practice (coordination of health care, assessment, education, patient support, trauma prevention, recovery, health screenings, etc.). Use the \”PICOT Draft\” template to complete this assignment.

Use a national, state or local population health care database to research indicators of disparity. Choose a mortality/morbidity indicator to identify a clinical problem or issue that you want to explore pertaining to a population of focus. Use this indicator to begin to formulate a PICOT statement.

Refer to the \”Evidence-Based Practice Project Proposal – Assignment Overview\” document for an overview of the evidence-based practice project proposal assignments.

You are required to cite one peer-reviewed source to complete this assignment. Sources must be published within the last 5 years and appropriate for the NUR 550 Evidence-Based Practice Project Proposal – Assignment assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are not required to submit this assignment to LopesWrite.

PICOT Draft Sample Paper


Part 1: Propose a relevant nursing practice problem for an evidence-based practice project. Explain why you selected this topic and how it is relevant to advance nursing practice. Include one research article that demonstrates support for the nursing practice problem.

The prevalence of central line associated bloodstream infections (CLABSI) and the acquisition of multi-drug resistant bacterial organisms is a critical medical problem that requires proper, evidence-backed intervention. A study by Lin et al. (2017 NUR 550 Evidence-Based Practice Project Proposal – Assignment) established a CLABSI incidence rate of 3.93 per 1000 central catherter days, with the dominant causative factors being Gram-negative (39.2%) and Gram-positive (33.2%) bacteria, as well as Candida spp. (27.6%). Given the heavy burden associated with these conditions, largely in terms of prolonged hospital stay, increased mortality and morbidity, I found it necessary to explore the topic and establish better ways of handling such infections among patients admitted in the intensive care unit.

Part II: In the table below, describe the population and the intervention. (You will continue drafting the PICOT, completing the shaded areas in Topic 3.)

PICOT Question
P Population Patients admitted to the Intensive care unit are in critical condition and are at increased risk of infection. This is attributed to the debilitating effects of their underlying condition and the life-saving procedures performed on them such as insertion of the central venous catheter and urinary catheter. Infections in this population can lead to prolonged hospital stay, increased cost of care, morbidity, and mortality. Early antibiotic use for suspected infections has been critical in reducing the effects of infection. However, antibiotic resistance develops in the long term. NUR 550 Evidence-Based Practice Project Proposal – AssignmentThe most common infection in the ICU is due to methicillin-resistant staphylococcus aureus (MRSA) and other gram-positive bacteria. Further, hospital-acquired pneumonia is a prevalent disease in this population. Septicemia and blood infections are prevalent and can lead to increased mortality if not controlled. Organisms get into the body through central lines, ventilators, and urinary catheters.

In a translational study by Mody (2018), the author sought to establish the relationship between indwelling devices in ICU patients and the occurrence of infection. Survey, randomized study, and observational study were used. The results showed that indwelling catheters increased the risk of bacterial colonization in most patients thus leading to the increased hospital stay, mortality, and increased cost of care.

I Intervention Chlorhexidine Gluconate is a local solution that has a bactericidal effect on gram-positive bacteria. It has a fast onset of action, prolonged duration, and is effective on broad spectrum bacteria. The application of chlorhexidine helps in reducing the entry of skin microflora into the bloodstream hence reduced infection.A study by Zamir et al. (2020 NUR 550 Evidence-Based Practice Project Proposal – Assignment) revealed that the use of chlorhexidine in ICU patients leads to a reduced rate of infection from 6.6% to 4.8% per 1000 patients admitted to the ICU. The study also established that reduced manipulation of the catheter will reduce the rate of infection. Chlorhexidine locking solution has been used to reduce manipulation of the central venous catheter and the result proved the efficiency of chlorhexidine in reducing the infection rate.
C Comparison
O Outcome
T Timeframe
Problem Statement

NUR 550 Evidence-Based Practice Project Proposal – Assignment  References

  • Lin, K-Y., Cheng, A., Chang, Y-C., Hung, M-C., Wang, J-T., Sheng, W-H., Hseuh, P-R., Chen, Y-C. & Chang, S-C. (2017). Central line-associated bloodstream infections among critically-ill patients in the era of bundle care. Journal of Microbiology, Immunology and Infection, 50(3), 339-348.
  • Mody, L. (2018). Translational models of infection prevention and control: lessons from studying high risk aging populations. Current Opinion in Infectious Diseases, 31(4), 359–367.
  • Zamir, N., Pook, M., McDonald, E., & Fox-Robichaud, A. E. (2020). Chlorhexidine locking device for central line infection prevention in ICU patients: protocol for an open-label pilot and feasibility randomized controlled trial. Pilot and Feasibility Studies, 6(1), 26.

See NRS 550 Topic 2 Discussions Biostatistics Here