NUR 550 Translational Research Graphic Organizer GCU

Translational Research PICOT Project

The purpose of this assignment is to conduct a comparison of different research designs to better understand their designs and application. Understanding the different types of research design is important so that nurses can effectively apply evidence-based research into practice to address issues and offer better patient care.

You will utilize your approved nursing practice problem to complete the evidence-based practice project proposal assignments for this course and NUR-590, during which you will synthesize all of the sections into a final written paper detailing your evidence-based practice project proposal.

Review feedback from your instructor on your \”Evidence-Based Practice Project Proposal: Identification of Nursing Practice Problem,\” submitted in Topic 1. If your original proposed nursing problem was outside the scope of nursing practice or not conducive to an evidence-based practice project proposal, work with your instructor to identify a new topic prior to beginning this assignment. If your proposed topic requires revision, complete this prior to beginning this NUR 550 Translational Research Graphic Organizer GCU assignment.

Conduct a literature search on your approved nursing practice problem. Find two translational research articles, one quantitative article, and one qualitative article. Using the \”Translational Research Graphic Organizer,\” present your proposed topic and, in the tables provided, compare one translational study to the quantitative study, and one translational study to the qualitative study.

Refer to the \”Evidence-Based Practice Project Proposal – Assignment Overview\” document for an overview of the evidence-based practice project proposal NUR 550 Translational Research Graphic Organizer GCU assignments.

You are required to cite four peer-reviewed sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the NUR 550 Translational Research Graphic Organizer GCU assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are not required to submit this NUR 550 Translational Research Graphic Organizer GCU assignment to LopesWrite.

Translational Research Graphic Organizer Sample Paper

State the nursing practice problem for your evidence-based practice project. If your nursing problem has not yet been approved, make any required changes or revisions to your nursing practice problem prior to starting the assignment. Using your proposed topic, conduct a literature search and complete the tables below.

Nursing Practice Problem: Central Line associated blood stream Infection (CLABSI)

Comparison 1: Translational Research vs. Qualitative Research

Criteria	Peer-Reviewed Translational Article and Permalink/ Working Link: Zamir, N., Pook, M., McDonald, E., & Fox-Robichaud, A. E. (2020). Chlorhexidine locking device for central line infection prevention in ICU patients: protocol for an open-label pilot and feasibility randomized controlled trial. Pilot and Feasibility Studies, 6(1), 26. https://doi.org/ 10.1186/s40814- 020-0564-9. Translational Research Type: interventional	Peer-Reviewed Traditional Article and Permalink/Working Link: Scheck McAlearney, A., Hefner, J. L., Robbins, J., Harrison, M. I., & Garman, A. (2017). Preventing central line-associated bloodstream infections: a qualitative study of management practices. Infection Control and Hospital Epidemiology: The Official Journal of the Society of Hospital Epidemiologists of America, 36(5), 557–563. https://doi.org/ 10.1017/ice.2015.27 Traditional Qualitative Research Type: extensive case study	Observations (Similarities/Differences)
Methodology	The study was done in 3 ICUs at Hamilton General hospital. A randomized control design was used. The study population was 100. Of the 100 patients, 50 were used as control while the other 50 were used in the study (Zamir et al., 2020). A chlorehexidine locking tool was used in 50 patients while the other half were subjected to usual care. The usual care included flushing the central line using 0.9% normal saline and maintaining hygiene. Those included in the study were >18 years, had a central venous catheter in situ, with no history of active infection, those with first ICU admission, and were expected to stay in for >72 hours in ICU. Those with active infection, allergic to chlorehexidine, and those who stayed for less than 72 hours were excluded.	The study was conducted in 8 US hospitals. Three hospitals were chosen based on their effort in preventing central line infections (Scheck et al., 2017). Low and high performing hospitals were compared. An extensive case study was performed. Transcribed verbatim interviews were used.	Randomized control trial was used in the translational study unlike the case study that was performed in qualitative study. Both studies aimed at reducing the rate of central line infections.
Goals	The primary goal was to test the feasibility of chlorehexidine locking device in ICU patients. The efficacy of the device was also tested. The secondary goal was to evaluate the uptake of the device among ICU nurses.	The goal was to identify different factors that could explain disparities in infection prevention among different levels of hospitals.	The translational study conducted a trial of a device to reduce the rate of infection. The results of the study would be used to determine if the tool could be employed in large population study. However, in both studies, infection prevention was the major goal.
Data Collection	Voluntary survey was used to collect data. The nurses who cared for the patient provided the data. A paper-based survey was administered to nurses in ICU. Additionally, the participants’ blood was collected every 48 hours for culture. Data from culture results was collected and stored using electronic health record.	In depth interviews were administered to administrators, clinical teams, nurses, and physicians.	Nurses who are the cornerstone of patient care were involved in both cases. Unlike in qualitative study where in-depth interviews were used, the translational study used surveys. Human specimen including blood was used for culture in translational study and this helped in identifying specific organism. NUR 550 Translational Research Graphic Organizer GCU

Comparison 2: Translational Research vs. Quantitative Research

Criteria	Peer-Reviewed Translational Article and Permalink/Working Link: Patel, P. K., Greene, M. T., Jones, K., Rolle, A. J., Ratz, D., Snyder, A., Saint, S., & Chopra, V. (2019). Quantitative results of a national intervention to prevent central line-associated bloodstream infection: A pre-post observational study: A pre-post observational study. Annals of Internal Medicine, 171(7_Suppl), S23–S29. https://doi.org/ 10.7326/M18-3533 Translational Research Type: interventional	Peer-Reviewed Traditional Article and Permalink/Working Link: Lin, K.-Y., Cheng, A., Chang, Y.-C., Hung, M.-C., Wang, J.-T., Sheng, W.-H., Hseuh, P.-R., Chen, Y.-C., & Chang, S.-C. (2017). Central line-associated bloodstream infections among critically-ill patients in the era of bundle care. Wei Mian Yu Gan Ran Za Zhi [Journal of Microbiology, Immunology, and Infection], 50(3), 339–348. https://doi.org/ 10.1016/j.jmii. 2015.07.001 Traditional Quantitative Research Type: Prospective.	Observations (Similarities/Differences)
Methodology	A total of 462 hospitals were recruited into the study in 4 cohorts. 24 hospitals within the district of Colombia that reported high rates of HAIs were also included. Both rural based and urban hospitals were included. Clustered and nonrandomized study designs were used (Patel et al., 2019). Pre and post interventional results were compared. the interventions used included evidence proven device to reduce HAIs, educational videos, webinar teachings, and expert involvement. The study was carried in acute, long-term care and ICU settings.	The study was carried out in national Taiwan University Hospital in Taiwan. A prospective surveillance study was performed on 181 patients admitted in ICU. The effectiveness of prevention was assessed. The bundle included hand hygiene, antisepsis of skin using chlorehexidine, dressing catheter site, and maximal barrier protection (Lin et al., 2017). The patients included were those with indwelling CVC and above 18 years of age. Monitoring of the patient was done from point of central line insertion up to either discharge from ICU, removal of central line, or death of the patient.	The translational study was done in several hospitals while the quantitative study was done in a single hospital. Clustered and nonrandomized study designs were used in translational study while prospective surveillance was used in quantitative study. In both cases, the researchers assessed the effectiveness of different prevention strategies.
Goals	The goal was to evaluate the impact of multimodal approach in reducing the rate of hospital acquired infections in hospitals that reported high hospital acquired infection	The goals were to assess the rate of CLABSI among patients admitted in ICU, to identify different organisms that cause CLABSI, and to determine the effectiveness of bundle care in reducing CLABSI incidences.	The goals of two studies varied in a number of ways. For instance, the translational study aimed at evaluating the effectiveness of multimodal approach in infection prevention, while the quantitative study aimed at identifying the cases and causative organisms.
Data Collection	Tabulations were used to collect data on the utilization of the device. Hospital data on the rate of infection pre and post intervention were used.	The researchers collected data using standardized case record. Active surveillance by infection control practitioner was performed to collect data on demography, ICU type, catheter type, length of ICU stay, and the causative organism in every case of CLABSI. Medical records of patients were also reviewed to find the diagnosis and clinical presentation of the patient prior to admission in the ICU.	Data was tabulated in translational study while standardized record was use in quantitative study. However, in both studies, the respective researchers used hospital data on patients to find further information about the patient. NUR 550 Translational Research Graphic Organizer GCU