NUR 550 EBP PICOT Final Paper

NUR 550 EBP PICOT Final Paper

PICOT (Population/Problem, Intervention, Comparison, Outcome, and Time to achieve the outcome) is a method that helps clarify the qualities needed to create a good question out of a practice issue or problem affecting a population of focus.

NUR 550 EBP PICOT Final Paper

The purpose of this assignment is to complete your PICOT for your selected nursing practice problem. Refer to your \”Evidence-Based Practice Project Proposal: Identification of Nursing Practice Problem\” assignment from Topic 1 to complete this assignment. If your nursing practice problem or PICOT required revision, include those revisions in this assignment. The final PICOT you develop in this assignment will provide the framework for developing your evidence-based practice project proposal. Use the \”PICOT-Final\” template to complete this NUR 550 EBP PICOT Final Paper assignment.

Refer to the \”Evidence-Based Practice Project Proposal – Assignment Overview\” document for an overview of the evidence-based practice project proposal assignments.

You are required to cite at least four peer-reviewed sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

PICOT Final Sample Paper


Complete your PICOT using your approved proposed nursing practice problem. If they were approved, you may use the population and intervention developed in your Topic 1 assignment. Include any necessary revisions in this submission. Refer to the “Example PICOT” below as needed for guidance on how to complete the PICOT. NUR 550 EBP PICOT Final Paper

PICOT Question
P Population Patients admitted in Intensive care unit, with central line catheter
I Intervention Use of chlorohexidine
C Comparison Flushing with normal saline
O Outcome Reduction in central line-associated bloodstream infections
T Timeframe 6 months
PICOTCreate a complete PICOT statement. In patients admitted in ICU with a central line catheter (P), how does the use of chlorhexidine (I) compared with flushing central line using normal saline (C) lead to the reduced central line-associated bloodstream infection (O) over six months (T)? NUR 550 EBP PICOT Final Paper
Problem StatementCreate a problem statement for your PICOT. You will use this problem statement throughout your final written NUR 550 EBP PICOT Final Paper paper.


Patients admitted to ICU are at an increased risks of developing central line-associated blood stream infections (CLABSI) (Bell & O’Grady, 2017). According to Haddadin et al. (2020), critically ill ICU patients tend to have weakened immunity due to the nature of their conditions, a factor that necessitates implantation with central line catheters to supply the necessary medication, nutrition, and hemodialysis. These factors increase the incidence of CLABSI. According to Jayaweera and Sivakumar (2020 NUR 550 EBP PICOT Final Paper), CLABSI leads to an increased hospital stay, suffering, pain, increased cost, high morbidity and mortality among patients. Failure to adhere to bundle care safety practices can increase the incidences of CLABSI. Chlorhexidine and normal saline solutions are often used to clean and flush central lines to reduce the likelihood of CLABSI (Lin et al., 2017). However, the two solutions differ in their modes of action and coverage to reduce the incidences of CLABSI.


  • Bell, T., & O’Grady, N. P. (2017). Prevention of central line-associated bloodstream infections. Infectious Disease Clinics of North America31(3), 551–559.
  • Haddadin, Y., Annamaraju, P., & Regunath, H. (2020). Central line associated blood stream infections. In StatPearls. StatPearls Publishing.
  • Jayaweera, J. A. A. S., & Sivakumar, D. (2020). Asymptomatic central line-associated bloodstream infections in children implanted with long term indwelling central venous catheters in a teaching hospital, Sri Lanka. BMC Infectious Diseases20(1), 457.
  • Lin, W.-P., Chang, Y.-C., Wu, U.-I., Hung, M.-C., Chuang, P.-Y., Wang, J.-T., Sheng, W.-H., Chen, Y.-C., & Chang, S.-C. (2017). Multimodal interventions for bundle implementation to decrease central line-associated bloodstream infections in adult intensive care units in a teaching hospital in Taiwan, 2009-2013. Wei Mian Yu Gan Ran Za Zhi [Journal of Microbiology, Immunology, and Infection]51(5), 644–651.

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